Endocrine Abstracts

Objective: The aim of this study is the characterizing of genetic variation in PvuII and XbaI polymorphisms of the ESR1 gene associated with age-dependent endocrine, metabolic and cognitive changes in a representative sample of Romanian population stratified by age and sex.Subjects and methods: Subjects, both genders aged between 20 and 80 yr were assigned to three lots 1) 177 subjects aged 55–80 years with moderately cognitive impairment (MCI) (MMS...

Objective: An on-going epidemiological populational study examined hormone balance during aging in women, and – whether there was a difference in endogenous serum sex hormone levels between a postmenopausal women group with moderately cognitive impairment and healthy age-mached women group.Subjects and methods: One hundred and sixty-three women aged 25 to 80 years were classified into three groups: (1) 44 subjects aged 55–80 years with moderate...